DNA double strand Ab,extractable fractionNuclear Ab Screen。请问这些都是什么项目?怎么理解这些检查结果?

JOURNAL MENUFIND ISSUES
FIND ARTICLES
GET ACCESS
FOR CONTRIBUTORS
ABOUT THIS JOURNAL
SPECIAL FEATURES
Vincenzo Costanzo1,*, Jayanta Chaudhuri2,*, Jennifer C Fung3,* andJohn V Moran4,*DOI:&10.1038/embor.
EMBO reports pages 837&842, Author Information1Genome Stability, London Research Institute, South Mimms, Hertfordshire, UK2Immunology Program, Memorial Sloan Kettering Cancer Center, New York, New York, USA3Department of Obstetrics, Gynecology and Reproductive Sciences, University of California, San Francisco, California, USA4Howard Hughes Medical Institute, Departments of Human Genetics and Internal Medicine, University of Michigan Medical School, Ann Arbor, Michigan, USA*Corresponding authors. Tel: +44 (0); Fax: +44 (0); E-mail:
or Tel: +1 646 888 2357; Fax: +1 646 422 0453; E-mail:
or Tel: +1 415 514 4309; Fax: +1 415 514 4242; E-mail:
or Tel: +1 734 615 0456; Fax: +1 734 763 3784; E-mail: Publication HistoryIssue online: 1 AUG 2009Version of Record online: 17 JUL 2009Manuscript Accepted: 23 JUN 2009Manuscript Received: 21 MAY 2009
ARTICLE TOOLS
References
M (2009) Chromosomal translocations induced at specified loci in human stem cells. Proc Natl Acad Sci USA 106: 10620&10625,,,
Eckersdorff
DO (2008) Mre11 nuclease activity has essential roles in DNA repair and genomic stability distinct from ATM activation. Cell 135: 85&96,,,
J et al (2007) Evolution of the immunoglobulin heavy chain class switch recombination mechanism. Adv Immunol 94: 157&214,,
Geisberger
MS (2009) The stability of AID and its function in class-switching are critically sensitive to the identity of its nuclear-export sequence. Proc Natl Acad Sci USA 106: 6736&6741,,,
B (2009) Genome-wide control of the distribution of meiotic recombination. PLoS Biol 7: 327&339,,
St Charles
J (2009) Impact of a hypomorphic Artemis disease allele on lymphocyte development, DNA end processing, and genome stability. J Exp Med 206: 893&908,,,
SC (2008) Identification of Holliday junction resolvases from humans and yeast. Nature 456: 357&361,,,,
MJ (2006) Initiation of meiotic recombination by formation of DNA double-strand breaks: mechanism and regulation. Biochem Soc Trans 34: 523&525,,,
JR (2007) A DNA replication mechanism for generating nonrecurrent rearrangements associated with genomic disorders. Cell 131: 1235&1247,,,
SC (2004) Happy Hollidays: 40th anniversary of the Holliday junction. Nat Rev Mol Cell Biol 5: 937&944,,,
JR (2009) Genomic disorders ten years on. Genome Med 1: 42,,,
LS (2008) Sae2, Exo1 and Sgs1 collaborate in DNA double-strand break processing. Nature 455: 770&774,,,,
Petersen-Mahrt
SK (2004) Activation-induced cytidine deaminase deaminates 5-methylcytosine in DNA and is expressed in pluripotent tissues: implications for epigenetic reprogramming. J Biol Chem 279: 52353&52360,,,
T (2007) Discovery of activation-induced cytidine deaminase, the engraver of antibody memory. Adv Immunol 94: 1&36,,
K (2009) Trans-regulation of mouse meiotic recombination hotspots by Rcr1. PLoS Biol 7: 340&349,,
San-Martin
Nussenzweig
Nussenzweig
MC (2007) The role of activation-induced deaminase in antibody diversification and chromosome translocations. Adv Immunol 94: 75&107,,
T (2008) E3 ligase activity of BRCA1 is not essential for cell viability of homology-directed repair of double-strand DNA breaks. Proc Natl Acad Sci USA 105: 20876&20881,,,
de Villartay
JP (2005) The repair of DNA damages/modifications during the maturation of the immune system: lessons from human primary immunodeficiency disorders and animal models. Adv Immunol 87: 237&295,,,
DF et al (2008) AID is required for the chromosomal breaks in c-myc that lead to c-myc/IgH translocations. Cell 135: 1028&1038,,,
DO (2006) DNA double-strand break repair: a relentless hunt uncovers new prey. Cell 124: 260&262,,,
MR (2008) Human chromosomal translocations at CpG sites and a theoretical basis for their lineage and stage specificity. Cell 135: 1130&1142,,,
SJ (2009) NBA1, a new player in the Brca1 A complex, is required for DNA damage resistance and checkpoint control. Genes Dev 23: 729&739,,,
M (2007) Formation of NHEJ-derived reciprocal chromosomal translocations does not require Ku70. Nat Cell Biol 9: 978&981,
G (2008) Sgs1 helicase and two nucleases DNA2 and Exo1 resect DNA double-strand break-induced gene conversion. Cell 134: 981&994,,,114网址导航J Clin Pathol. 1987 N 40(11): .
PMCID: PMC1141244Detection of antibodies to double stranded DNA and extractable nuclear antigen. and
This article has been
other articles in PMC.Full text is available as a scanned copy of the original print version. Get a printable copy (PDF file) of the
(1.6M), or click on a page image below to browse page by page. Links to PubMed are also available for .
Click on the image to see a larger version.These references are in PubMed. This may not be the complete list of references from this article. Schwartz RS, Stollar BD. Origins of anti-DNA autoantibodies. J Clin Invest. 1985 F75(2):321–327. []
[]Hardin JA, Mimori T. Autoantibodies to ribonucleoproteins. Clin Rheum Dis. 1985 D11(3):485–505.
[]Shero JH, Bordwell B, Rothfield NF, Earnshaw WC. High titers of autoantibodies to topoisomerase I (Scl-70) in sera from scleroderma patients. Science. 1986 Feb 14;231(–740.
[]FARR RS. A quantitative immunochemical measure of the primary interaction between I BSA and antibody. J Infect Dis. 1958 Nov-D103(3):239–262.
[]Isenberg DA, Dudeney C, Williams W, Addison I, Charles S, Clarke J, Todd-Pokropek A. Measurement of anti-DNA antibodies: a reappraisal using five different methods. Ann Rheum Dis. 1987 J46(6):448–456. []
[]Somerfield SD, Roberts MW, Booth RJ. Double-stranded DNA antibodies: a comparison of four methods of detection. J Clin Pathol. 1981 S34(9):. []
[]Sharp GC, Irvin WS, LaRoque RL, Velez C, Daly V, Kaiser AD, Holman HR. Association of autoantibodies to different nuclear antigens with clinical patterns of rheumatic disease and responsiveness to therapy. J Clin Invest. 1971 F50(2):350–359. []
[]Articles from Journal of Clinical Pathology are provided here courtesy of BMJ Group
)- subscription required
Show all items
Show all items
Show all items
Show all items
Show all items
Show all items
Show all items
Show all items
Show all items
Show all items
Show all items
Show all items
Show all items
Show all items
Show all items
Show all items
CitePeer Related Articles

我要回帖

更多关于 lagging strand 的文章

 

随机推荐