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维生素C硒缺乏对孕妇和胎儿的影响
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---华夏经纬网版权所有---你知道维生素D还能减肥和降血糖吗？
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|个人分类:|系统分类:|关键词:维生素，减肥药
由国际内分泌学会与美国内分泌学会联合举行的ICE/ENDO 2014国际会议上，美国贝勒医学院的S. Sisley在会上报告称：“维生素D缺乏在肥胖者及2型糖尿病人中很常见，但人们并不知道维生素D缺乏是否会引起这些疾病”。人和大鼠等啮齿动物一样，大脑中的下丘脑区域掌管着体重与血糖，而维生素D受体就位于此处。研究人员在肥胖大鼠中分别进行了维生素D活化及强效形式——1,25-二羟维生素D3短期给药和长期给药的药效评价，评价指标包括体重、血糖、葡萄糖耐量等。在短期试验中，先让大鼠禁食4小时，再测定禁食血糖含量，然后给12只处理组肥胖大鼠下丘脑部位导入维生素D，而给14只对照组肥胖大鼠下丘脑部位仅导入溶剂。结果显示，维生素D能使肥胖大鼠耐受葡萄糖的能力提高，也就是胰岛素敏感性增强，不再出现血糖过度升高现象。在长期试验中，通过4周给药发现，用药肥胖大鼠的食量和体重双双下降。在第28天测量时，肥胖大鼠的食量降低了3倍，而体重减少了24%。这项研究的结论是，维生素D可以抑制食欲、降低血糖和减轻体重，其机理是通过结合下丘脑控制中枢的维生素D受体，增强胰岛素受体对胰岛素的敏感性，提高葡萄糖耐受性，保持相对恒定的血糖水平。因此，那些经常服用多种维生素的人，补充维生素D不仅是补钙的辅助手段，无意中还能减肥和降血糖，应该是一举两得！不过，这还是动物实验结果，尚无人体试验数据，使用常规剂量是否有上述效果尚不得而知，有心者可以继续跟踪这个研究结果。Vitamin D can lower weight, blood sugar via the brain, study findsDate:Source:Endocrine SocietySummary:Vitamin D treatment acts in the brain to improve weight and blood glucose (sugar) control in obese rats, according to a new study. &Vitamin D deficiency occurs often in obese people and in patients with Type 2 diabetes, yet no one understands if it contributes to these diseases,& said the study's principal investigator. A region of the brain called the hypothalamus controls both weight and glucose, and has vitamin D receptors there.Vitamin D treatment acts in the brain to improve weight and blood glucose (sugar) control in obese rats, according to a new study being presented Saturday at the joint meeting of the International Society of Endocrinology and the Endocrine Society: ICE/ENDO 2014 in Chicago.&Vitamin D deficiency occurs often in obese people and in patients with Type 2 diabetes, yet no one understands if it contributes to these diseases,& said Stephanie Sisley, MD, the study's principal investigator and an assistant professor at Baylor College of Medicine, Houston. &Our results suggest that vitamin D may play a role in the onset of both obesity and Type 2 diabetes by its action in the brain.&&The brain is the master regulator of weight,& Sisley said. A region of the brain called the hypothalamus controls both weight and glucose, and has vitamin D receptors there.In this study funded by the National Institutes of Health, Sisley and partners at the University of Cincinnati delivered vitamin D directly to the hypothalamus. The investigators administered the active, potent form of vitamin D -- called 1,25-dihydroxyvitamin D3 -- to obese male rats through a cannula (thin tube) surgically inserted using anesthesia into the brain's third ventricle. This narrow cavity lies within the hypothalamus. Rats recovered their presurgery body weight, and the researchers verified the correct cannula placement.The animals received nothing to eat for four hours, so they could have a fasting blood sugar measurement. Afterward, 12 rats received vitamin D dissolved in a solution acting as a vehicle for drug delivery. Another 14 rats, matched in body weight to the first group, received only the vehicle, thus serving as controls. One hour later, all rats had a glucose tolerance test, in which they received an injection of dextrose, a sugar, in their abdomen, followed by measurement of their blood sugar levels again.Compared with the control rats, animals that received vitamin D had improved glucose tolerance, which is how the body responds to sugar. In a separate experiment, these treated rats also had greatly improved insulin sensitivity, the body's ability to successfully respond to glucose. When this ability decreases -- called insulin resistance -- it eventually leads to high blood sugar levels. Two of insulin's main effects are to clear glucose from the bloodstream and decrease glucose production in the liver. In this study, vitamin D in the brain decreased the glucose created by the liver.In a separate experiment of long-term vitamin D treatment, the researchers gave three rats vitamin D and four rats vehicle alone for four weeks. They observed a large decrease in food intake and weight in rats receiving vitamin D compared with the group that did not get vitamin D. Over 28 days, the treated group ate nearly three times less food and lost 24 percent of their weight despite not changing the way they burned calories, study data showed. The control group did not lose any weight.&Vitamin D is never going to be the silver bullet for weight loss, but it may work in combination with strategies we know work, like diet and exercise,& Sisley commented.She said more research is necessary to determine if obesity alters vitamin D transport into the brain or its action in the brain.Story Source:The above story is based on
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　　怎么降血糖?对于糖尿病患者而言，降血糖是很重要的一件事，但是降血糖不能服用过激的药物，还要通过饮食的控制来调理。吃什么降血糖好，这是很多高血糖的人会问到的问题。下面小编给大家推荐几种比较常见的降糖食物……
　　取丝瓜200克，茶叶适量，将丝瓜切片煮熟，再加茶叶冲泡，每日1次。
　　冬瓜、西瓜
　　取冬瓜皮、西瓜皮各100克，瓜蒌根250克，加水煎1小时，去渣再将汤用文火浓缩为黏稠样，每次10克，代茶饮。
　　南瓜中含有能抑制葡萄糖吸收的果糖，这种果糖可与人体内多余的胆固醇结合，从而起到降低胆固醇、预防动脉硬化的作用。南瓜中还含有胡芦巴碱、腺嘌呤、戊聚糖、甘露醇等许多对人体有益的物质，有促进胰岛素分泌的作用。其具体的服食方法是：取南瓜100克，加水煮熟后食用，每天吃一次。
　　黄瓜具有除热止渴的作用。黄瓜的糖含量仅为1.6名，所以黄瓜可作为糖尿病患者的代用食品。此外，黄瓜中还含有维生素c、胡萝卜素、纤维素和矿物质等，其所含的丙醇二酸能抑制人体内糖类物质转变为脂肪。合并有高血压的肥胖型糖尿病患者若每天吃100克黄瓜，可使其病情得到改善。
　　苦瓜富含多种营养成分，尤其是维生素c的含量高居各种瓜品之首。苦瓜中所含的苦瓜皂甙不仅有类似胰岛素的作用，而且还可刺激胰岛素的分泌，堪称“植物胰岛素”。应用苦瓜皂甙制剂治疗2型糖尿病的总有效率可达78.3%。苦瓜的食用方法是：取苦瓜1个，洗净、去瓤后切片，加水煮熟后一次吃完，每天吃1～2次。
　　如果你也喜欢养生，可以加我微信maka13000
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